Non-Replicative Vector Platforms


Non-replicative vectors can minimize immune responses triggered by viral vectors, making them a promising option for patients with pre-existing immunity to certain viruses.As the scope of gene therapy expands to address various genetic disorders and diseases, non-replicative vector platforms offer versatility for delivering different therapeutic genes.


EG 427’s use of a non-replicative Herpes Simplex Virus type 1 (nrHSV-1) based vector platform demonstrates the trend of exploring novel delivery systems and vector platforms for gene therapy and DNA medicine. Non-replicative vectors offer advantages in safety and precision.


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